|
Laboratory
for Experimental Nuclear Medicine (LENM)
The Laboratory for Experimental Nuclear Medicine has two
sections:
The section of Radiobiology and Experimental Radionuclide
Therapy is involved with the biophysical consequences of radioactive
decay and its application to cancer therapy. Members have
examined cell survival, transformation and DNA damage resulting
from the dense ionization produced by cascades of auger and
Koster-Cronig electrons as well as alpha particles. The therapeutic
response to radionuclides emitting these particles and attached
to targeting carriers, such as pyrimidine deoxynucleosides,
is being studied in animal tumors of the brain, spinal cord,
lung, ovary and bladder.
The section of Radiopharmaceutical Chemistry and Radiopharmacy
is concerned with the development of new radiodiagnostic agents.
Members explore the basic chemistry of the radio-element technetium
and its application to radiopharmaceutical design. They look
for novel applications of radioactive compounds to the solution
of medical problems
|