LGD-4033, also called Ligandrol or Anabolicum, is a drug used for repairing worn out muscles caused by neuromuscular diseases or dystrophy. It acts by increasing muscle mass. It’s from the family of selective androgen receptor modulators. Here we will review the effects of this drug on the cardiovascular system, bone health, and muscle density.
In muscle wasting diseases (MWD) the muscle density are decreased and also very weak which would eventually affect the cardiovascular system and bone health. The heart and bones have major roles to play in MWD as cardiac diseases and osteoporosis affect muscle density.
Why LGD-4033? Ligandrol binds with the androgen receptor found in the body. Androgens are found predominantly in males and scarcely in females.
LGD-4033 helps to increase lean muscle mass in muscle wasting diseases. Aging is a natural process, as we age the integrity of the muscles is lost as the muscle becomes weak and lean. Ligandrol use can restore muscle strength.
Below are the uses of Ligandrol.
Uses of LGD-4033
Aging can cause a drop in muscle density and muscle mass. In a clinical study carried out on 30 old people, 15 male and 15 females from the same community. 15 were given a 3mg loading dosage of LGD-4033 for a period of eight weeks while the other 15 were given a lower dosage of LGD-4033 for the same period of time. It was found that the set given a higher dosage had significant changes such as increased muscular strength, improved physical strength, and better cardiovascular outputs. Meanwhile, the other set had little or no significant changes.
Ligandrol is used in the management of neuromuscular diseases, geriatrics, and carcinoma patients.
Clinical research or study patterning muscle loss or dystrophy in cancer is still in view.
The cardiac cycle is one of the most complex cycles of the human body. The heart is a highly muscular organ with a musculoskeletal structure. LGD-4033 is essential to people who often suffer from muscle wasting and weight loss as a result of cardiac diseases.
In a clinical research which involved 10 patients suffering from cardiac distress. They took a loading dosage of Ligandrol (3mg) for three weeks and later reduced to a maintenance dosage (1mg) for five weeks. This resulted to a massive improvement in cardiac readings as there was a drop in cholesterol. The relationship between the lipid profile and the heart muscles is cholesterol when the lipids levels are healthy it prevents cardiovascular heart disease (CHD).
The bone is the framework on which the muscles are built. When there is a problem with the bone such as osteoporosis the muscles are weak and cannot build around the bone.
It has been proven that LGD-4033 improves bone health by increasing the minerals and therefore it leads to increased strength and bone density invariably. Naturally osteoporosis is a condition where there is decreased bone minerals leading to frailty in bones. Also, a decrease in bone mass could also be as a result of hormonal deficiency. Ligandrol acts like a hormone in the bones and muscles therefore increasing the bone mass to prevent possible muscle injuries or fracture.
A clinical study has been carried out successfully in rodents such as rats but not any human.
Below are the benefits of using Ligandrol.
Benefits of using Ligandrol
The benefits of using this drug would not only increase muscle mass but also help in anabolism. LGD-4033 acts very selectively and it does not alter other organ make up such as the liver. In fact, liver function tests(LFT) are intact and most importantly it also doesn’t target the kidney either. The blood pressure is also normal as most of its action is selective.
In clinical research the patients who ingested 3mg of Ligandrol in eight weeks have added weight of 3ibs in eight weeks not just the addition of weight but also increase in strength and response.
Safe to use
According to the doctors’ advice, LGD-4033 comes with two different dosing phrases i.e. the loading and maintenance. Ligandrol increases blood circulation to target organs like heart, kidney, and liver etc. which would relatively reduce blood pressure.
Side effects of LGD 4033
These effects are mainly as a result of wrong dosage plans or excessive usage (drug abuse) it could also be a sign that Ligandrol is not good for you. If you notice any of these effects kindly see a doctor.
- Pain in the testis
- Zero or no increase in muscles after 5 to 6 weeks
- Joint pains similar to arthritis
- Gastrointestinal disturbances
- Strength loss
- Erectile dysfunction
- Distorted vision
- High tension headache
- Irregular menstrual cycle
- Hair loss or alopecia
- Skin discoloration
These reviews are based on different clinical research or study carried out on patients. It has also proven the potency of the drug.
- No water retention in kidneys
- Muscle gain
- Improved liver function test
- Healthy neurology
- Healthy physiology
- Fat loss
- Better joint flexibility
- Hormonal balance
- No amenorrhea
- Good cardiac rhythm
- Tightness of loosed muscles
LGD-4033 has proven to be very efficient especially in muscle wasting diseases or dystrophy. Having a selective function it also helps the body regain loosed weight by carefully breaking down unnecessary fats via lipolysis. Ligandrol also known as Anabolicum as the name implies helps in anabolism and effective protein synthesis. As strength, agility and stamina are increased simultaneously this is as a result of an increase in bone and muscle mass.